Testing the stability of the benefit transfer function for discrete choice contingent valuation data

We examine the stability of the benefit transfer function across 42 recreational forests in the British Isles. A working definition of reliable function transfer is put forward, and a suitable statistical test is provided. The test is based on the sensitivity of the model log-likelihood to removal of individual forest recreation sites. We apply the proposed methodology on discrete choice contingent valuation data and find that a stable function improves our measure of transfer reliability, but not by much. We conclude that, in empirical studies on transferability, function stability considerations are secondary to the availability and quality of site attribute data. Modellers’ can study the advantages of transfer function stability vis-à-vis the value of additional information on recreation site attributes

Observations of Rapid Disk-Jet Interaction in the Microquasar GRS 1915+105

We present evidence that ~ 30 minute episodes of jet formation in the Galactic microquasar GRS 1915+105 may sometimes entirely be a superposition of smaller, faster phenomena. We base this conclusion on simultaneous X-ray and infrared observations in July 2002, using the Rossi X-ray Timing Explorer and the Palomar 5 meter telescope. On two nights, we observed quasi-periodic infrared flares from GRS 1915+105, each accompanied by a set of fast oscillations in the X-ray light curve (indicating an interaction between the jet and accretion disk). In contrast to similar observations in 1997, we find that the duration of each X-ray cycle matches the duration of its accompanying infrared flare, and we observed one instance in which an isolated X-ray oscillation occurred at the same time as a faint infrared "subflare" (of duration ~ 150 seconds) superimposed on one of the main flares. From these data, we are able to conclude that each X-ray oscillation had an associated faint infrared flare and that these flares blend together to form, and entirely comprise, the ~ 30 minute events we observed. Part of the infrared emission in 1997 also appears to be due to superimposed small flares, but it was overshadowed by infrared-bright ejections associated with the appearance of a sharp "trigger" spike in each X-ray cycle that were not present in 2002. We also study the evolution of the X-ray spectrum and find significant differences in the high energy power law component, which was strongly variable in 1997 but not in 2002. Taken together, these observations reveal the diversity of ways in which the accretion disk and jet in black hole systems are capable of interacting and solidify the importance of the trigger spike for large ejections to occur on ~ 30 minute timescales in GRS 1915+105.Comment: 17 pages, 9 figures; accepted for publication in The Astrophysical Journa

Infrared Spectroscopy of Nearby Radio Active Elliptical Galaxies

In preparation for a study of their circumnuclear gas we have surveyed 60% of a complete sample of elliptical galaxies within 75 Mpc that are radio sources. Some 20% of our nuclear spectra have infrared emission lines, mostly Paschen lines, Brackett γ, and [Fe II]. We consider the influence of radio power and black hole mass in relation to the spectra. Access to the spectra is provided here as a community resource

Pesticide Use in Northern Ireland’s Arable Crops from 1992–2016 and Implications for Future Policy Development

Publication history: Accepted - 31 July 2018; Published online - 8 August 2018Since the 1960s, the objective for the United Kingdom (UK) government policy and legislation on crop protection practices has been to minimise the impact of pesticide use in agriculture and horticulture to the wider environment. Subsequent European Union (EU) policy and legislation have also targeted this objective through a demanding approvals process, competency tests for users, maximum residue limits, regular post-registration monitoring and the promotion of integrated pest and disease management techniques. However, none of this substantive regulation refers to target reduction levels for pesticide use. Since 1992, the number of arable farms in Northern Ireland has decreased by 61% with a consequent reduction of 34% in the area of arable crops grown. Despite this reduction in area of arable crops grown, the area treated by the major pesticide groups increased by 49% due to intensification, but the weight of major pesticides applied to arable crops decreased by 37%. However, the intensity of application measured by the total quantity of all pesticides applied to the basic area of arable crops treated remained relatively constant at approximately 3.2 kg/ha. Pesticide usage trends and reduction policies in other geographic regions are also discussed for comparative purposes.Our funding providers, the Department of Agriculture, Environment and Rural Affairs, Northern Ireland and the Department of Environment, Food and Rural Affairs, Great Britain

Can we bridge the gap? Knowledge and practices related to Diabetes Mellitus among general practitioners in a developing country: A cross sectional study

<p>Abstract</p> <p>Background</p> <p>Diabetes mellitus is becoming a serious public health problem in Sri Lanka and many other developing countries in the region. It is well known that effective management of diabetes reduces the incidence and progression of many diabetes related complications, thus it is important that General Practitioners (GPs) have sound knowledge and positive attitudes towards all aspects of its management. This study aims to assess knowledge, awareness and practices relating to management of Diabetes Mellitus among Sri Lankan GPs.</p> <p>Methods</p> <p>A cross-sectional study was conducted among all 246 GPs registered with the Ceylon College of General Practitioners using a pre-validated self-administered questionnaire.</p> <p>Results</p> <p>205 responded to the questionnaire(response rate 83.3%). Their mean duration of practice was 28.7 ± 11.2 years. On average, each GP had 27 ± 25 diabetic-patient consultations per-week. 96% managed diabetic patients and 24% invariably sought specialist opinion. 99.2% used blood glucose to diagnose diabetes but correct diagnostic cut-off values were known by only 48.8%. Appropriate use of HbA1c and urine microalbumin was known by 15.2% and 39.2% respectively. 84% used HbA1c to monitor glyceamic control, while 90.4% relied on fasting blood glucose to monitor glyceamic control. Knowledge on target control levels was poor.</p> <p>Nearly 90% correctly selected the oral hypoglyceamic treatment for obese as well as thin type 2 diabetic patients. Knowledge on the management of diabetes in pregnancy was poor. Only 23.2% knew the correct threshold for starting lipid-lowering therapy. The concept of strict glycaemic control in preference to symptom control was appreciated only by 68%. The skills for comprehensive care in subjects with multiple risk factors were unsatisfactory.</p> <p>Conclusions</p> <p>The study was done among experienced members of the only professional college dedicated to the specialty. However, we found that there is room for improvement in their knowledge and practices related to diabetes. We recommend continuing medical education and training programs to update GP's knowledge in order to improve health outcomes in this group of patients.</p

Socioeconomic status and polycystic ovary syndrome

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common metabolic-endocrine disorder in women and is associated with a number of metabolic morbidities. We examined the association of PCOS and its components with socioeconomic status (SES) over the life course to explore the role of the environment on the development of PCOS. METHODS: Participants included 1163 women, aged 34-39, from the Coronary Artery Risk Development in Young Adults (CARDIA) Women\u27s Study, examined at year 16 of the CARDIA study (2001). PCOS was defined according to the 1990 National Institutes of Health (NIH) criteria. RESULTS: Logistic regression models, adjusted for age, body mass index (BMI), waist circumference, and oral contraceptive (OC) use, demonstrated a statistically significant association between those women with low parental education/high personal education and PCOS (odds ratio [OR] 2.5, 95% confidence interval [CI] 1.4-4.4). CONCLUSIONS: Our results indicate that women who experienced low childhood SES are at increased risk of PCOS, but this risk is limited to those who have personally attained a high level of education. More research is needed to determine the childhood socioeconomic factors that might influence this risk and whether conditions associated with upward life mobility play a role or if this group of at-risk women is simply more likely to recall the symptoms that define PCOS

The Spectra of T Dwarfs I: Near-Infrared Data and Spectral Classification

We present near-infrared spectra for a sample of T dwarfs, including eleven new discoveries made using the Two Micron All Sky Survey. These objects are distinguished from warmer (L-type) brown dwarfs by the presence of methane absorption bands in the 1--2.5 \micron spectral region. A first attempt at a near-infrared classification scheme for T dwarfs is made, based on the strengths of CH$_4$ and H$_2$O bands and the shapes of the 1.25, 1.6, and 2.1 \micron flux peaks. Subtypes T1 V through T8 V are defined, and spectral indices useful for classification are presented. The subclasses appear to follow a decreasing T$_{eff}$ scale, based on the evolution of CH$_4$ and H$_2$O bands and the properties of L and T dwarfs with known distances. However, we speculate that this scale is not linear with spectral type for cool dwarfs, due to the settling of dust layers below the photosphere and subsequent rapid evolution of spectral morphology around T$_{eff}$ $\sim$ 1300--1500 K. Similarities in near-infrared colors and continuity of spectral features suggest that the gap between the latest L dwarfs and earliest T dwarfs has been nearly bridged. This argument is strengthened by the possible role of CH$_4$ as a minor absorber shaping the K-band spectra of the latest L dwarfs. Finally, we discuss one peculiar T dwarf, 2MASS 0937+2931, which has very blue near-infrared colors (J-K$_s$ = $-0.89\pm$0.24) due to suppression of the 2.1 \micron peak. The feature is likely caused by enhanced collision-induced H$_2$ absorption in a high pressure or low metallicity photosphere.Comment: 74 pages including 26 figures, accepted by ApJ v563 December 2001; full paper including all of Table 3 may be downloaded from http://www.gps.caltech.edu/~pa/adam/classification ;also see submission 010844

Infective Endocarditis: A Review of the Past and Present, and a Look into the Future

Infective endocarditis is a lethal and challenging multifaceted disease that can involve any vascularized system. We believe that multimodality imaging is invaluable to provide a comprehensive diagnosis. Our management approach to infective endocarditis adheres to a combination of the AHA, ACC, STS, and ESC guidelines. With the rapidly increasing transcatheter valve population, we expect an increased caseload of infective endocarditis. Beyond patients with hemorrhagic strokes, we advocate for early surgery if medical management has failed. Furthermore, a multidisciplinary team approach is imperative in infective endocarditis, and clear communication reduces the time to diagnosis and definitive treatment for this patient population

SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection

Given high SARS-CoV-2 incidence, coupled with slow and inequitable vaccine roll-out in many settings, there is a need for evidence to underpin optimum vaccine deployment, aiming to maximise global population immunity. We evaluate whether a single vaccination in individuals who have already been infected with SARS-CoV-2 generates similar initial and subsequent antibody responses to two vaccinations in those without prior infection. We compared anti-spike IgG antibody responses after a single vaccination with ChAdOx1, BNT162b2, or mRNA-1273 SARS-CoV-2 vaccines in the COVID-19 Infection Survey in the UK general population. In 100,849 adults median (50 (IQR: 37–63) years) receiving at least one vaccination, 13,404 (13.3%) had serological/PCR evidence of prior infection. Prior infection significantly boosted antibody responses, producing higher peak levels and/or longer half-lives after one dose of all three vaccines than those without prior infection receiving one or two vaccinations. In those with prior infection, the median time above the positivity threshold was >1 year after the first vaccination. Single-dose vaccination targeted to those previously infected may provide at least as good protection to two-dose vaccination among those without previous infection